CLINICAL PAPERS

Sylfirm X is clinically proven to successfully treat a range of indications on the face and body. Enter your details below to browse our library of clinical papers, demonstrating Sylfirm X’s effectiveness and safety.

Electromagnetic Initiation and Propagation of Bipolar Radiofrequency Tissue Reactions via Invasive Non-Insulated Microneedle Electrode

Authors: Jongju Na, Zhenlong Zheng, Christopher Dannaker, Sang Eun Lee, Jin-Soo Kang, and Sung Bin Cho
Objective: The study investigates how bipolar radiofrequency (RF) energy is initiated and propagated in biological tissues when delivered via invasive, non-insulated microneedle electrodes. It aims to analyse RF-induced tissue reactions and the patterns of thermal coagulation in both in vivo and ex vivo models.

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Synergistic Effect of 300 µm Needle-Depth Fractional Microneedling Radiofrequency on the Treatment of Senescence-Induced Aging Hyperpigmentation of the Skin

Authors: Young In Lee 1,2,† , Eunbin Kim 1,† , Dong Won Lee 3 , Jemin Kim 1,2 , Jihee Kim 1,2, Won Jai Lee 3 and Ju Hee Lee 1,2,*
Objective: The study explores the synergistic effect of 300 μm needle-depth fractional microneedling radiofrequency (FMR) combined with Q-switched Nd:YAG laser (QSNY) in treating aging-induced hyperpigmentation (such as melasma and senile lentigo). It was found that adding FMR significantly improves pigmentation, reduces wrinkles, and enhances skin rejuvenation compared to QSNY alone.

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Invasive Pulsed-Type, Bipolar, Alternating Current Radiofrequency Treatment Using Microneedle Electrodes for Nasal Rosacea

Authors: Tae Hwan Ahn, Sung Bin Cho
Objective: The study evaluates the effectiveness and safety of invasive pulsed-type, bipolar alternating current (AC) radiofrequency (RF) treatment using microneedle electrodes for nasal rosacea. It presents two case studies of patients treated with this method.

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PW, Efficacy Assessment of a Pulsed-Type Bipolar Radiofrequency Microneedling Device for Treating Facial Acne Vulgaris Using a Skin-Color Imaging System: A Pilot Study

Authors: Tae Woong Seul, Jong Heon Park, Jae Young Kim, Hwa Jung Ryu
Objective: This study evaluates the efficacy and safety of a pulsed-type bipolar radiofrequency (RF) microneedling device for treating facial acne vulgaris and post-inflammatory erythema (PIE). A novel skin-colour imaging system was used for objective assessment

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Innovative Therapeutic Approaches to Hair Loss Treatment Using SYLFIRM X

Author: Hyeon Gyeong Kim, MD, South Korea
Objective: The paper discusses the effectiveness of the SYLFIRM X system, a pulsed and continuous-wave bipolar radiofrequency (RF) microneedling device, in treating hair loss (alopecia). It explores the device’s mechanism of action, clinical trials, and treatment protocols.

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Successful Treatment of Refractory Melasma Using Invasive Micro-Pulsed Electric Signal Device

Authors: Moon Choi, Seohee Choi, Jin-Soo Kang, Sung Bin Cho
Objective: The study investigates the efficacy and safety of Invasive Micro-Pulsed Electric Signal (IMPES) therapy for treating melasma resistant to conventional treatments, specifically low-fluence Q-switched Nd:YAG laser (LFQSNY) and topical lightening agents (TLA).

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